Consortium on the Neurobiology of Adolescent Drinking in Adulthood (NADIA) Research Resource (Collaborative U24 - Clinical Trial Not Allowed) | RFA AA 20 005

Opportunity Information: Apply for RFA AA 20 005

The Consortium on the Neurobiology of Adolescent Drinking in Adulthood (NADIA) Research Resource funding opportunity (RFA-AA-20-005) is a National Institutes of Health initiative led by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) that uses a cooperative agreement mechanism (U24) to support a larger, coordinated research consortium. The core purpose of this U24 is not to run an independent research project in isolation, but to operate as a shared research resource that provides technical and scientific support to multiple NADIA research projects funded under companion U01 awards. In practical terms, the U24 functions as a hub that strengthens, standardizes, and accelerates the consortium's science by supplying centralized capabilities, expertise, and infrastructure that individual U01 teams would struggle to build alone.

Scientifically, the NADIA consortium is focused on a specific and high-impact question: how alcohol exposure during adolescence can lead to persistent, long-lasting changes in the brain and in brain-driven behavior that are still evident in adulthood. The emphasis is on complex brain function-behavior relationships, meaning the consortium is interested in how neural systems, circuitry, and neurobiological processes translate into measurable behavioral outcomes over time, and how adolescent drinking may alter those links in durable ways. The long-term framing matters because it targets enduring neurobiological consequences, not just short-term intoxication effects or immediate adolescent outcomes.

As a cooperative agreement, this U24 implies substantial involvement from the NIH/NIAAA in coordinating and steering aspects of the program alongside awardees, which is typical when the funding agency wants active partnership to ensure that consortium components align, share data or tools effectively, and meet common milestones. The FOA is explicitly labeled "Clinical Trial Not Allowed," indicating that supported activities should not include clinical trials as defined by NIH policy. The expected role is resource-oriented support for the consortium's research, such as harmonizing methodologies, enabling cross-site comparability, facilitating data management and sharing, providing specialized analyses or platforms, or other collaborative functions that help the U01 projects work together as a unified program.

Eligibility is broad across U.S.-based organizational types commonly allowed in NIH funding, including state, county, and local governments; special districts; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; tribal organizations other than federally recognized governments; public housing authorities/Indian housing authorities; nonprofits with or without 501(c)(3) status (excluding higher education institutions where applicable); for-profit organizations other than small businesses; and small businesses. The FOA also highlights additional eligible applicant categories often emphasized by NIH for inclusivity and reach, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISI), as well as faith-based or community-based organizations, eligible federal agencies, regional organizations, and U.S. territories or possessions.

At the same time, the geographic and organizational limitations are clear: non-domestic (non-U.S.) entities are not eligible to apply as applicant organizations, non-domestic components of U.S. organizations are not eligible, and foreign components are not allowed under the NIH Grants Policy Statement definition. In other words, the work and organizational footprint supported by this award must remain fully domestic, without foreign institutional participation as a funded component.

Administratively, the opportunity is categorized as discretionary funding and falls under the health activity area, with CFDA number 93.273. The original closing date listed for the opportunity was December 18, 2019, and the posting indicates it was created on September 23, 2019. While the text notes NIAAA's intent to renew the initiative through this FOA, applicants would still be expected to follow the cooperative, consortium-support model: building a resource that directly enables and enhances the NADIA U01 research projects and advances the consortium-wide goal of understanding how adolescent alcohol exposure can produce lasting neurobiological and behavioral consequences into adulthood.

• The National Institutes of Health in the health sector is offering a public funding opportunity titled "Consortium on the Neurobiology of Adolescent Drinking in Adulthood (NADIA) Research Resource (Collaborative U24 - Clinical Trial Not Allowed)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.273.
• This funding opportunity was created on 2019-09-23.
• Applicants must submit their applications by 2019-12-18. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

Apply for RFA AA 20 005

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